Circulating CD40+ and CD86+ B Cell Subsets Demonstrate Opposing Associations With Risk of Stroke.

Summary, in English

Accumulating evidence shows that immune cells play an important role in atherosclerosis. Most attention has focused on the role of different T cell subsets, whereas the possible involvement of B cells has been less studied. In this study, we assessed the association of 2 different B cell subsets, CD19(+)CD40(+) and CD19(+)CD86(+) B cells, with risk for development of acute cardiovascular events.

• Författare: Polyxeni Mantani; Irena Ljungcrantz; Linda Andersson; Ragnar Alm; Bo Hedblad; Harry Björkbacka; Jan Nilsson; Gunilla Nordin Fredrikson
• Avdelning/ar: Kardiovaskulär forskning - immunitet och ateroskleros; Kardiovaskulär forskning - epidemiologi; EXODIAB: Excellence of Diabetes Research in Sweden; EpiHealth: Epidemiology for Health
• Publiceringsår: 2014
• Språk: Engelska
• Sidor: 211-211
• Publikation/Tidskrift/Serie: Arteriosclerosis, Thrombosis and Vascular Biology
• Volym: 34
• Issue: 1
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/24202305?dopt=Abstract; http://dx.doi.org/10.1161/ATVBAHA.113.302667
• Dokumenttyp: Artikel i tidskrift
• Förlag: Lippincott Williams & Wilkins
• Ämne: Cardiac and Cardiovascular Systems
• Status: Published
• Forskningsgrupp: Cardiovascular Research - Immunity and Atherosclerosis; Cardiovascular Research - Epidemiology
• ISBN/ISSN/Övrigt: ISSN: 1524-4636