Regulation of PMP22 mRNA by G3BP1 affects cell proliferation in breast cancer cells.
Författare
Summary, in English
Regulation of mRNAs is one way to control protein levels and thereby important cellular processes such as growth, invasion and apoptosis. G3BPs constitute a family of mRNA-binding proteins, shown to be overexpressed in several cancer types, including breast, colon and pancreas cancer. G3BP has been reported to both stabilize and induce degradation of specific mRNAs.
Avdelning/ar
- Institutionen för translationell medicin
- Experimentell patologi, Malmö
- Cancerimmunologi, Malmö
- BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
Publiceringsår
2013
Språk
Engelska
Publikation/Tidskrift/Serie
Molecular Cancer
Volym
12
Issue
1
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
BioMed Central (BMC)
Ämne
- Cancer and Oncology
Status
Published
Forskningsgrupp
- Experimental Pathology, Malmö
- Cancer Immunology, Malmö
ISBN/ISSN/Övrigt
- ISSN: 1476-4598