Webbläsaren som du använder stöds inte av denna webbplats. Alla versioner av Internet Explorer stöds inte längre, av oss eller Microsoft (läs mer här: * https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Var god och använd en modern webbläsare för att ta del av denna webbplats, som t.ex. nyaste versioner av Edge, Chrome, Firefox eller Safari osv.

Predominance of caudate nucleus lesions in acute ischemic stroke patients with impairments in language and speech

In English

Författare

Summary, in English

Background and purpose. Whereas traditional views of language processing in the brain have assumed that the language function is concentrated to a limited number of cortical areas (Broca’s and Wernicke’s areas), current knowledge points at a much more complex system of language and speech processing involving many brain areas, both cortical and subcortical. The purpose of the current study was to make an unbiased assessment of which cerebral areas are affected in first-ever acute ischemic stroke patients identified as having language and speech impairments according to the National Institute of Health Stroke Scale (NIHSS).

Methods. Data from thirty-four patients with language and speech impairments, with a score of 1-3 on item 9 on the NIHSS, following ischemic stroke was collected from the Lund Stroke Register. MRI images acquired up to 20 days after stroke onset were used to create an overlap lesion image using MRIcron software.

Results. The classical language areas, Wernicke’s and Broca’s area, were affected in less than one fourth of the patients. The most frequently affected region was a subcortical region - the left caudate nucleus and the adjacent corona radiata.

Conclusions. These findings contribute to the growing body of evidence that the basal ganglia have a crucial role in the control over language and speech processing.

Publiceringsår

2016

Språk

Engelska

Sidor

148-153

Publikation/Tidskrift/Serie

European Journal of Neurology

Volym

23

Issue

1

Dokumenttyp

Artikel i tidskrift

Förlag

Wiley-Blackwell

Ämne

  • Radiology, Nuclear Medicine and Medical Imaging
  • General Language Studies and Linguistics
  • Neurology

Nyckelord

  • caudate nucleus
  • stroke
  • speech
  • language
  • MRI
  • basal ganglia

Status

Published

Projekt

  • Humanities and Medicine (HuMe)
  • Images of tones: fMRI-studies on the processing of prosody in the human brain

Forskningsgrupp

  • Clinical Stroke Research Group

ISBN/ISSN/Övrigt

  • ISSN: 1351-5101