Increased plasma level of soluble urokinase plasminogen activator receptor is associated with incidence of heart failure but not atrial fibrillation.

Summary, in English

Soluble urokinase plasminogen activator receptor (suPAR) in plasma is a novel inflammatory marker thought to be released from the cell surface of neutrophils, T cells, and macrophages. Other inflammatory markers, mainly acute phase proteins produced in the liver, have been associated with the incidence of heart failure (HF) and atrial fibrillation (AF). We investigated the association between suPAR and incident HF and AF in a population-based cohort.

• Författare: Yan Borné; Margaretha Persson; Olle Melander; Gustav Smith; Gunnar Engström
• Avdelning/ar: Kardiovaskulär forskning - epidemiologi; Internmedicin - epidemiologi; Kardiovaskulär forskning - hypertoni; Kardiologi; EXODIAB: Excellence of Diabetes Research in Sweden; EpiHealth: Epidemiology for Health
• Publiceringsår: 2014
• Språk: Engelska
• Sidor: 377-383
• Publikation/Tidskrift/Serie: European Journal of Heart Failure
• Volym: 16
• Issue: 4
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/24464777?dopt=Abstract; http://dx.doi.org/10.1002/ejhf.49
• Dokumenttyp: Artikel i tidskrift
• Förlag: Elsevier
• Ämne: Cardiac and Cardiovascular Systems
• Status: Published
• Forskningsgrupp: Cardiovascular Research - Epidemiology; Internal Medicine - Epidemiology; Cardiovascular Research - Hypertension
• ISBN/ISSN/Övrigt: ISSN: 1879-0844