Human endogenous peptide p33 inhibits detrimental effects of LL-37 on osteoblast viability.
Författare
Summary, in English
High levels of the antimicrobial peptide, LL-37, are detected in gingival crevicular fluid from patients with chronic periodontitis. LL-37 not only shows antimicrobial activity but also affects host-cell viability. The objective of the present study was to identify endogenous mechanisms that antagonize the detrimental effects of LL-37 on osteoblast viability, focusing on the human peptide p33 expressed on the surface of various cell types.
Publiceringsår
2015
Språk
Engelska
Sidor
80-88
Publikation/Tidskrift/Serie
Journal of Periodontal Research
Volym
50
Issue
1
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Wiley-Blackwell
Ämne
- Dentistry
Status
Published
Projekt
- Effects of the antimicrobial peptide LL-37 on host cell viability
Forskningsgrupp
- Vascular Physiology
ISBN/ISSN/Övrigt
- ISSN: 1600-0765