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Are urinary PAHs biomarkers of controlled exposure to diesel exhaust?

In English

Författare

Summary, in English

Urinary polycyclic aromatic hydrocarbons (PAHs) were evaluated as possible biomarkers of exposure to diesel exhaust (DE) in two controlled-chamber studies. We report levels of 14 PAHs from 28 subjects in urine that were collected before, immediately after and the morning after exposure. Using linear mixed-effects models, we tested for effects of DE exposure and several covariates (time, age, gender and urinary creatinine) on urinary PAH levels. DE exposures did not significantly alter urinary PAH levels. We conclude that urinary PAHs are not promising biomarkers of short-term exposures to DE in the range of 106-276 mu g/m(3).

Publiceringsår

2014

Språk

Engelska

Sidor

332-339

Publikation/Tidskrift/Serie

Biomarkers

Volym

19

Issue

4

Dokumenttyp

Artikel i tidskrift

Förlag

Taylor & Francis

Ämne

  • Environmental Health and Occupational Health

Nyckelord

  • diesel exhaust
  • Biomarker
  • PAHs
  • polycyclic aromatic hydrocarbons
  • urine

Status

Published

ISBN/ISSN/Övrigt

  • ISSN: 1366-5804