Can genetics improve precision of therapy in diabetes?

Summary, in English

Diabetes mellitus is a lifelong, incapacitating disease affecting multiple organs. Presently, type 2 diabetes (T2D) can neither be prevented nor cured and the disease is associated with devastating chronic complications. These complications impose an immense burden on the quality of life of patients and account for about 12% of direct health care costs in Europe. Genetic analysis will increase our understanding of this heterogeneous disease and may help offer more personalized treatment.

• Författare: Leif Groop; Petter Storm; Anders Rosengren
• Avdelning/ar: Translationell Muskel Forskning; Diabetes - öpatofysiologi; EXODIAB: Excellence of Diabetes Research in Sweden
• Publiceringsår: 2014
• Språk: Engelska
• Sidor: 440-443
• Publikation/Tidskrift/Serie: Trends in Endocrinology and Metabolism
• Volym: 25
• Issue: 9
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/25028244?dopt=Abstract; http://dx.doi.org/10.1016/j.tem.2014.06.005
• Dokumenttyp: Artikel i tidskrift
• Förlag: Elsevier
• Ämne: Endocrinology and Diabetes
• Nyckelord: ANDIS; diabetes; diabetics
• Status: Published
• Forskningsgrupp: Genomics, Diabetes and Endocrinology; Diabetes - Islet Patophysiology
• ISBN/ISSN/Övrigt: ISSN: 1879-3061