Webbläsaren som du använder stöds inte av denna webbplats. Alla versioner av Internet Explorer stöds inte längre, av oss eller Microsoft (läs mer här: * https://www.microsoft.com/en-us/microsoft-365/windows/end-of-ie-support).

Var god och använd en modern webbläsare för att ta del av denna webbplats, som t.ex. nyaste versioner av Edge, Chrome, Firefox eller Safari osv.

Expression of Multiple Functional RNAs or Proteins from One Viral Vector.

In English

Författare

Summary, in English

In this chapter, we will cover the available design choices for enabling expression of two functional protein or RNA sequences from a single viral vector. Such vectors are very useful in the neuroscience-related field of neuronal control and modulation, e.g., using optogenetics or DREADDs, but are also desirable in applications of CRISPR/Cas9 in situ genome editing and more refined therapeutic approaches. Each approach to achieving this combined expression has its own strengths and limitations, which makes them more or less suitable for different applications. In this chapter, we describe the available alternatives and provide tips on how they can be implemented.

Publiceringsår

2016

Språk

Engelska

Sidor

41-56

Publikation/Tidskrift/Serie

Methods in Molecular Biology

Volym

1382

Dokumenttyp

Artikel i tidskrift

Förlag

Springer

Ämne

  • Cell and Molecular Biology

Status

Published

Forskningsgrupp

  • Molecular Neuromodulation

ISBN/ISSN/Övrigt

  • ISSN: 1940-6029