Nonsense Mutations in the Shelterin Complex Genes ACD and TERF2IP in Familial Melanoma.
Författare
Summary, in English
The shelterin complex protects chromosomal ends by regulating how the telomerase complex interacts with telomeres. Following the recent finding in familial melanoma of inactivating germline mutations in POT1, encoding a member of the shelterin complex, we searched for mutations in the other five components of the shelterin complex in melanoma families.
Avdelning/ar
- BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
- Medicinsk onkologi
- Bröstcancer-genetik
- Kirurgi, Lund
- EpiHealth: Epidemiology for Health
Publiceringsår
2015
Språk
Engelska
Sidor
408-408
Publikation/Tidskrift/Serie
Journal of the National Cancer Institute
Volym
107
Issue
2
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Oxford University Press
Ämne
- Cancer and Oncology
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 1460-2105