First case of type E wound botulism diagnosed using real-time PCR.
Författare
Summary, in English
Wound botulism is a growing problem among injecting drug users. The condition is often difficult to diagnose, with laboratory confirmation in only 50% of the cases. Here we present a real-time PCR-based method for the diagnosis of wound botulism caused by Clostridium botulinum. The assay includes an internal amplification control which is amplified simultaneously with the genes encoding neurotoxin types A, B, and E. This method was used to detect the first case of wound botulism in an injecting drug user in Sweden. In addition, to the best of our knowledge, this is the first reported case of wound botulism caused by C. botulinum type E.
Avdelning/ar
- Avdelningen för medicinsk mikrobiologi
- Teknisk mikrobiologi
- Infectious Diseases Research Unit
- Socialmedicin och global hälsa
- Institutionen för kliniska vetenskaper, Malmö
Publiceringsår
2007
Språk
Engelska
Sidor
3589-3594
Publikation/Tidskrift/Serie
Journal of Clinical Microbiology
Volym
45
Issue
11
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
American Society for Microbiology
Ämne
- Microbiology in the medical area
Status
Published
Forskningsgrupp
- Infectious Diseases Research Unit
- Social Medicine and Global Health
ISBN/ISSN/Övrigt
- ISSN: 1098-660X