Supported liquid membrane extraction of urinary trans, trans-muconic acid, a biomarker for benzene exposure
Författare
Summary, in English
In this study, sample preparation of urinary trans, trans-muconic acid (tt-MA), a minor metabolite and biomarker of benzene, by means of Supported Liquid Membrane (SLM) extraction has been investigated. The sample extract was automatically transferred on-line to an ion exchange chromatographic column and the analytes were detected using a photodiode array detector. Automation of the system was accomplished using a robotic sample preparation processor integrated into the chromatographic system. Detection limits calculated from the baseline noise was in the sub-ppb range, and quantification of tt-MA is safe down to 10 ppb.
Avdelning/ar
Publiceringsår
2002
Språk
Engelska
Sidor
351-355
Publikation/Tidskrift/Serie
Journal of Separation Science
Volym
25
Issue
5-6
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
John Wiley & Sons Inc.
Ämne
- Analytical Chemistry
Nyckelord
- extraction
- supported liquid membrane
- benzene exposure
- biomarker
- muconic acid
- urine analysis
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 1615-9314