Antibiotic stewardship challenges in the management of community-acquired infections for prevention of escalating antibiotic resistance

Summary, in English

Community-acquired infections, including respiratory tract infections (RTIs) and urinary tract infections (UTIs), represent a major burden for most healthcare systems, partially due to ineffective or inappropriate antibiotic treatment leading to clinical failure, which often requires alternative antibiotics for cure. Appropriate antimicrobial use not only maximises clinical success in the treatment of community-acquired infections, but also minimises unintended consequences such as resistance development or collateral damage. This article outlines a range of antibiotic stewardship strategies and other preventative approaches that support the management of community-acquired infections, based on existing antibiotic use for community-acquired infections and the current resistance patterns among common RTI and UTI pathogens. (C) 2014 The Authors. Published by Elsevier Ltd on behalf of International Society for Chemotherapy of Infection and Cancer.

• Författare: Javier Garau; Dave P. Nicolau; Björn Wullt; Matteo Bassetti
• Avdelning/ar: Avdelningen för mikrobiologi, immunologi och glykobiologi - MIG
• Publiceringsår: 2014
• Språk: Engelska
• Sidor: 245-253
• Publikation/Tidskrift/Serie: Journal of Global Antimicrobial Resistance
• Volym: 2
• Issue: 4
• Länkar: http://dx.doi.org/10.1016/j.jgar.2014.08.002
• Dokumenttyp: Artikel i tidskrift
• Förlag: Elsevier
• Ämne: Immunology in the medical area; Microbiology in the medical area
• Nyckelord: Antibiotic stewardship; Antibiotic resistance; Community-acquired; infection
• Status: Published
• ISBN/ISSN/Övrigt: ISSN: 2213-7165