Bacterial aetiology in ventilator-associated pneumonia at a Swedish university hospital
Författare
Summary, in English
Ventilator-associated pneumonia (VAP) is a common complication of respiratory support and is associated with increased mortality, morbidity and costs, and a prolonged stay in the intensive care unit. Scandinavian data on the aetiology in VAP are lacking. We hereby present a retrospective study on the aetiology of VAP diagnosed by protective specimen brush culture at Malmo University Hospital in relation to early-and late-onset VAP, antibiotic treatment and the incidence of drug-resistant bacteria. Patients registered with a diagnosis of VAP between January 2004 and September 2007 were included in the study. Sixty-five of 109 patients diagnosed with VAP met the inclusion criteria, and 103 bacterial isolates were cultured from these patients. The most common findings among the 65 VAP episodes were Enterobacteriaceae (28), Pseudomonas aeruginosa (13), Haemophilus influenzae (12) and Staphylococcus aureus (8). Patients with no antibiotic treatment at the onset of VAP had significantly more H. influenzae (p = 0.035) and Gram-positive pathogenic bacteria (p = 0.019). There was no difference in incidence of P. aeruginosa between early-and late-onset VAP. Resistant bacteria were found in 18% of the patients.
Avdelning/ar
- Infectious Diseases Research Unit
- Klinisk mikrobiologi, Malmö
Publiceringsår
2010
Språk
Engelska
Sidor
469-474
Publikation/Tidskrift/Serie
Scandinavian Journal of Infectious Diseases
Volym
42
Issue
6-7
Dokumenttyp
Artikel i tidskrift
Förlag
Informa Healthcare
Ämne
- Infectious Medicine
Status
Published
Forskningsgrupp
- Infectious Diseases Research Unit
- Clinical Microbiology, Malmö
ISBN/ISSN/Övrigt
- ISSN: 1651-1980