Effect of feeding colostrum versus exogenous immunoglobulin G on gastrointestinal structure and enteric nervous system in newborn pigs
Författare
Summary, in English
Colostrum is an indispensable source of antibodies (IgG) protecting the newborn pig against infection. We studied the effect of feeding colostrum and purified IgG on early structure and development of the gastrointestinal tract (GIT). Newborn littermate pigs were fed either colostrum, an elemental diet (ED), or an ED supplemented with purified serum IgG (ED + IgG) for 24 h or then only ED up to 72 h. Afterwards, pigs were slaughtered. Colostrum-fed pigs or ED supplemented with IgG (ED + IgG) increased thickness (P < 0.001) of stomach mucosa and muscularis (P < 0.05) compared to the ED group not receiving IgG. Feeding an ED supplemented with IgG improved morphology of the GIT towards that of colostrum-fed piglets and indicates a beneficial effect of IgG on GIT development in neonatal pigs. Immunohistochemical studies indicate that ED feeding may influence the expression of nitric oxide synthase in jejunal myenteric (but not submucous) neurons of newborn pigs.
Avdelning/ar
Publiceringsår
2012
Språk
Engelska
Sidor
327-329
Publikation/Tidskrift/Serie
Journal of Animal Science
Volym
90
Dokumenttyp
Artikel i tidskrift
Förlag
Oxford University Press
Ämne
- Zoology
Nyckelord
- immunoglobulin G
- elementary diet
- colostrum
- gut development
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 1525-3163