Distinct gene expression signatures in lynch syndrome and familial colorectal cancer type x.

Summary, in English

Heredity is estimated to cause at least 20% of colorectal cancer. The hereditary nonpolyposis colorectal cancer subset is divided into Lynch syndrome and familial colorectal cancer type X (FCCTX) based on presence of mismatch repair (MMR) gene defects.

• Författare: Mev Dominguez; Christina Therkildsen; Srinivas Veerla; Mats Jönsson; Inge Bernstein; Åke Borg; Mef Nilbert
• Avdelning/ar: Bröstcancer-genetik; EpiHealth: Epidemiology for Health; BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
• Publiceringsår: 2013
• Språk: Engelska
• Publikation/Tidskrift/Serie: PLoS ONE
• Volym: 8
• Issue: 8
• Fulltext: - 3 MB; Download statistics
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/23951239?dopt=Abstract; http://dx.doi.org/10.1371/journal.pone.0071755
• Dokumenttyp: Artikel i tidskrift
• Förlag: Public Library of Science (PLoS)
• Ämne: Cancer and Oncology
• Status: Published
• Projekt: Precision Medicine in Hereditary Cancer and Sarcoma; targeted surveillance, immunotherapy and individualized follow-up
• ISBN/ISSN/Övrigt: ISSN: 1932-6203