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Respiratory and ocular symptoms in workers exposed to potassium aluminium-tetrafluoride soldering flux

In English

Författare

  • Britt Larsson
  • Jan-Eric Karlsson
  • Jörn Nielsen

Summary, in English

Objectives Exposure to aluminium compounds, such as fluorides in gaseous and particulate form, places people who work in potrooms at risk for respiratory symptoms. Workers in potrooms, however, also are exposed to a number of other air contaminants. In this study, we present the first report of a dose-response relationship after exposure to potassium aluminium tetrafluoride (KAlF4) and the influence of smoking and atopy. Materials All workers (308) from an industrial plant that used KA1F as soldering flux were invited to participate in the study. In all, 289 workers participated and 118 employees not exposed to chemicals in their professional work served as an unexposed group. Methods In the first step, all subjects answered a questionnaire concerning respiratory symptoms and work history, and participated in a lung function examination. In a second step, all workers who reported work-related complaints from lower respiratory airways were invited to participate in medical examination, methacholine test, screening test of respiratory allergy, and skin prick test against KAlF4. Results The exposed subjects had more symptoms than the unexposed group; dry cough odds ratio (OR): 5.17 (confidence interval 1.79-15.0), stuffy nose: 2.3 (1.25-4.22), nose bleeding: 10.7 (3.26-35.3) and ocular symptoms 5.01 (1.92-13.1) except for chest tightening and wheezing, and shortness of breath. The symptoms appeared in a dose response-like manner although the ORs between high and low exposed were significant for only chest tightening and wheezing, 2.62 (1.30-5.26) and stuffy nose 2.1 (1.22-3.66). Smokers and atopics did not report more frequent work-related symptoms. Smokers were significantly less hyperreactive than non-smokers, indicating a healthy-worker effect. No one showed a positive skin prick test against KAlF4. Conclusions In spite of exposure levels of KAlF4 well below the new Swedish threshold limit, value frequent respiratory and ocular symptoms were reported. No evidence of IgE mediated allergy was found.

Publiceringsår

2007

Språk

Engelska

Sidor

627-633

Publikation/Tidskrift/Serie

International Archives of Occupational and Environmental Health

Volym

80

Issue

7

Dokumenttyp

Artikel i tidskrift

Förlag

Springer

Ämne

  • Environmental Health and Occupational Health

Nyckelord

  • respiratory symptoms
  • ocular
  • increased
  • KAlF4
  • exposure

Status

Published

ISBN/ISSN/Övrigt

  • ISSN: 1432-1246