Presence of High-Risk HPV mRNA in Relation to Future High-Grade Lesions among High-Risk HPV DNA Positive Women with Minor Cytological Abnormalities.
Författare
Summary, in English
Continuous expression of E6- and E7-oncogenes of high-risk human papillomavirus (HPV) types is necessary for the development and maintenance of the dysplastic phenotype. The aim of the study was to determine the sensitivity and specificity of the APTIMA HPV mRNA assay (Hologic) in predicting future development of high-grade cervical intraepithelial neoplasia (CIN) among high-risk HPV-DNA-positive women with atypical squamous cells of undetermined significance (ASCUS) or low-grade squamous epithelial lesion (LSIL) cytology.
Publiceringsår
2015
Språk
Engelska
Publikation/Tidskrift/Serie
PLoS ONE
Volym
10
Issue
4
Fulltext
- Available as PDF - 160 kB
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Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Public Library of Science (PLoS)
Ämne
- Microbiology in the medical area
- Cell and Molecular Biology
- Cancer and Oncology
Status
Published
Forskningsgrupp
- Clinical Microbiology, Malmö
- Pathology, Malmö
ISBN/ISSN/Övrigt
- ISSN: 1932-6203