Sensitizing capacity of Disperse Orange 1 and its potential metabolites from azo reduction and their cross-reactivity pattern.

Summary, in English

Simultaneous contact allergies to Disperse Orange 1, 4-nitroaniline and p-aminodiphenylamine (PADPA), as well as to other disperse azo dyes and to p-phenylenediamine (PPD), have been reported. Cross-reactivity is one of the possible explanations for simultaneous reactions between PPD and disperse azo dyes. Some metabolites from the azo reduction of these disperse azo dyes could be sensitizers, as human skin bacteria produce azo reductases.

• Författare: Laura Malinauskiene; Erik Zimerson; Magnus Bruze; Kristina Morgardt-Ryberg; Marléne Isaksson
• Avdelning/ar: Yrkes- och miljödermatologi
• Publiceringsår: 2013
• Språk: Engelska
• Sidor: 40-48
• Publikation/Tidskrift/Serie: Contact Dermatitis
• Volym: 69
• Issue: 1
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/23782357?dopt=Abstract; http://dx.doi.org/10.1111/cod.12078
• Dokumenttyp: Artikel i tidskrift
• Förlag: Wiley-Blackwell
• Ämne: Dermatology and Venereal Diseases
• Status: Published
• Forskningsgrupp: Occupational and Environmental Dermatology
• ISBN/ISSN/Övrigt: ISSN: 0105-1873