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Comparative genomics helps to elucidate novel biochemical pathways

Publiceringsår: 2007
Språk: Engelska
Sidor: 369-372
Publikation/Tidskrift/Serie: Trends in Genetics
Volym: 23
Nummer: 8
Dokumenttyp: Artikel
Förlag: Elsevier


How well do we understand which enzymes are involved in the primary metabolism of the cell? A recent study using comparative genomics and postgenomics approaches revealed a novel pathway in the most studied organism, Escherichia coli. The analysis of a new operon consisting of seven previously uncharacterized genes thought to be involved in the degradation of nucleic acid precursors shows the impact of comparative genomics on the discovery of novel pathways and enzymes.



  • Biology and Life Sciences
  • genomics
  • biochemical pathways
  • nucleic acid precursors


  • ISSN: 0168-9479

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