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Antisense RNAs everywhere?

Publiceringsår: 2002
Språk: Engelska
Sidor: 223-226
Publikation/Tidskrift/Serie: Trends in Genetics
Volym: 18
Nummer: 5
Dokumenttyp: Artikel
Förlag: Elsevier


In recent years, systematic searches of both prokaryote and eukaryote genomes have identified a staggering number of small RNAs, the biological functions of which remain unknown. Small RNA-based regulators are well known from bacterial plasmids. They act on target RNAs by sequence complementarity; that is, they are antisense RNAs. Recent findings suggest that many of the novel orphan RNAs encoded by bacterial and eukaryotic chromosomes might also belong to a ubiquitous, heterogeneous class of antisense regulators of gene expression.



  • Biology and Life Sciences
  • bacteria
  • plasmid
  • riboregulator
  • antisense RNA
  • non-coding RNA
  • gene silencing


  • Flärdh
  • ISSN: 0168-9479
  • ISSN: 0168-9525

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