Cell proliferation, measured as flow cytometric S-phase fraction, is a strong prognostic indicator in FIGO stage I endometrioid endometrial carcinoma: a population-based study.

Summary, in English

In early-stage endometrial carcinoma, there is controversy regarding the prognostic value of the flow cytometric variables DNA ploidy (diploid vs. aneuploid) and S-phase fraction. In Sweden, the former is included in national guidelines despite poor scientific support and the latter is not used clinically. This study investigates the prognostic properties of these variables, together with classical histopathological variables, in multivariate analysis in a stringently stratified material.

• Författare: Rasmus W Green; Sanna Engblom; Bo Baldetorp; Linda Werner Hartman; Anna Måsbäck; Maria Bjurberg
• Avdelning/ar: Tumörmikromiljö; Bröstcancer-genetik; Medicinsk onkologi
• Publiceringsår: 2015
• Språk: Engelska
• Sidor: 1064-1073
• Publikation/Tidskrift/Serie: Acta Obstetricia et Gynecologica Scandinavica
• Volym: 94
• Issue: 10
• Fulltext: - 721 kB; Download statistics
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/26123703?dopt=Abstract; http://dx.doi.org/10.1111/aogs.12704
• Dokumenttyp: Artikel i tidskrift
• Förlag: Wiley-Blackwell
• Ämne: Cancer and Oncology
• Status: Published
• ISBN/ISSN/Övrigt: ISSN: 1600-0412