Simultaneous detection of molecular oxygen and water vapor in the tissue optical window using tunable diode laser spectroscopy
Författare
Summary, in English
We report on a newly developed diode-laser spectroscopic system for gas detection in scattering
media. Two pigtailed diode lasers are used, operating in a wavelength modulation scheme, to
simultaneously detect molecular oxygen at 760 nm and water vapour at 935 nm within the tissue
optical window (600 nm to 1.3 μm). Different modulation frequencies are used to distinguish
between the two wavelengths. No crosstalk can be observed between the gas contents of the two gas
channels. The system is made compact by using a computer board and performing software based
lock-in detection. The noise floor obtained corresponds to an absorption fraction of about 6 · 10−5
for both oxygen and water vapour. The power of the technique is illustrated by preliminary results
from a clinical trial investigating the human sinuses.
media. Two pigtailed diode lasers are used, operating in a wavelength modulation scheme, to
simultaneously detect molecular oxygen at 760 nm and water vapour at 935 nm within the tissue
optical window (600 nm to 1.3 μm). Different modulation frequencies are used to distinguish
between the two wavelengths. No crosstalk can be observed between the gas contents of the two gas
channels. The system is made compact by using a computer board and performing software based
lock-in detection. The noise floor obtained corresponds to an absorption fraction of about 6 · 10−5
for both oxygen and water vapour. The power of the technique is illustrated by preliminary results
from a clinical trial investigating the human sinuses.
Avdelning/ar
Publiceringsår
2008
Språk
Engelska
Sidor
2028-2034
Publikation/Tidskrift/Serie
Applied Optics
Volym
47
Issue
12
Fulltext
Dokumenttyp
Artikel i tidskrift
Förlag
Optical Society of America
Ämne
- Cancer and Oncology
Status
Published
Forskningsgrupp
- Biophotonics
ISBN/ISSN/Övrigt
- ISSN: 2155-3165