Meny

Du är här

A new tomographic technique for absolute measurements of white and gray matter blood flow

Författare:
Publiceringsår: 2003
Språk: Engelska
Sidor: 323-323
Publikation/Tidskrift/Serie: Journal of the International Neuropsychological Society
Volym: 9
Nummer: 2
Dokumenttyp: Konferensbidrag
Förlag: Cambridge University Press

Sammanfattning

The integrity of the white matter is as important as that of the gray matter and white matter pathology has commonly been reported in elderly subjects and in patients with organic dementia. The aim of the present study is to develop and evaluate an improved method for reliable tomographic measurements of absolute white and gray matter blood flow. The new tomographic method (modified Xe-SPECT) is based on an extension of the period of 133Xe inhalation from one to eight minutes followed by 22 instead of four minutes of breathing of ambient air. This gives a markedly enhanced signal from the white matter and better basis for correct quantification pf the blood flow. The arrival and clearance of the tracer are recorded by a three head gamma camera system that provides flow maps with a spatial resolution of about one cm. The new method has been evaluated in healthy younger and older (around 70 years) subjects as well as in a group of elderly patients with organic dementia. Our preliminary findings indicate that new and clinically valuable information is obtained by the improved Xe-SPECT method.

Disputation

Nyckelord

  • Social Sciences

Övriga

The Thirty-First Annual International Neuropsychological Society Conference
2003-02-05/2003-02-08
Honolulu, Hawaii, USA
Published
Yes
  • ISSN: 1469-7661
  • ISSN: 1355-6177

Box 117, 221 00 LUND
Telefon 046-222 00 00 (växel)
Telefax 046-222 47 20
lu [at] lu [dot] se

Fakturaadress: Box 188, 221 00 LUND
Organisationsnummer: 202100-3211
Om webbplatsen