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Progress in miniaturisation of proteon arrays - a step closer to high-density nanoarrays

Publiceringsår: 2007
Språk: Engelska
Sidor: 813-819
Publikation/Tidskrift/Serie: Drug discovery today
Volym: 12
Nummer: 19-20
Dokumenttyp: Artikel

Sammanfattning

Protein microarrays is a technology with great promise for high-throughput proteomics. Designing high-performance protein microarrays for global proteome analysis has, however, turned out to be challenging. To this end, major efforts are under way to design novel array formats capable of harboring the tremendous range of probes required to target complex proteomes composed of more than 10 000 analytes. By adopting nanotechnology, the first generation of miniaturized nanoarrays has recently emerged, which opens up new avenues for global proteome analysis and disease proteomics. This review describes the progress and key issues in designing miniaturized protein arrays.

Disputation

Nyckelord

  • Biology and Life Sciences

Övriga

Published
Yes
  • ISSN: 1359-6446

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