Biological effects and clinical efficacy of a topical Toll-like receptor 7 agonist in seasonal allergic rhinitis: a parallel group controlled phase IIa study.

Summary, in English

The purpose of the study was to examine effects of pre-treatment with a Toll-like receptor 7 (TLR7) agonist (AZD8848) in allergic rhinitis and to evaluate clinical effects of two dosing regimens.

• Författare: Lennart Greiff; Cecilia Ahlström-Emanuelsson; Mikaela Alenäs; Gun Almqvist; Morgan Andersson; Anders Cervin; Jan Dolata; Sam Lindgren; Anders S Mårtensson; Barbara Young; Henrik Widegren
• Avdelning/ar: Öron-, näs- och halssjukdomar, Lund; Kliniska Vetenskaper, Helsingborg
• Publiceringsår: 2015
• Språk: Engelska
• Sidor: 903-915
• Publikation/Tidskrift/Serie: Inflammation Research
• Volym: 64
• Issue: 11
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/26342289?dopt=Abstract; http://dx.doi.org/10.1007/s00011-015-0873-2
• Dokumenttyp: Artikel i tidskrift
• Förlag: Birkhäuser Verlag
• Ämne: Respiratory Medicine and Allergy
• Status: Published
• ISBN/ISSN/Övrigt: ISSN: 1420-908X