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Robustness of metabolic maps

In English

Författare

Summary, in English

With the ever increasing amount of genomic data available, the interest for generating biochemical pathways has grown tremendously. So far, mainly complete genomes have been used to reconstruct the biochemical pathways and their associated interactions. However, a large number of low coverage genomes, as well as other sources of partial genomic data, are currently available for many organisms. In order to be able to use incomplete data for metabolic reconstruction, the inherent properties of this procedure need to be investigated. In this short note, we describe the robustness and predictive power of metabolic reconstructions using partial information from Schizosaccharomyces pombe. We also discuss the implications of the results on reference genome projects as well as other large-scale sequencing data.

Publiceringsår

2004

Språk

Engelska

Sidor

589-593

Publikation/Tidskrift/Serie

Journal of Bioinformatics and Computational Biology

Volym

2

Issue

3

Dokumenttyp

Artikel i tidskrift

Förlag

World Scientific Publishing

Ämne

  • Biological Sciences

Nyckelord

  • Metabolic reconstructionmetabolic mapsgenome analysisrobustness analysisbiochemical pathways

Status

Published

Forskningsgrupp

  • Microbial Ecology

ISBN/ISSN/Övrigt

  • ISSN: 0219-7200