Du är här

Robustness of metabolic maps

Författare:
Publiceringsår: 2004
Språk: Engelska
Sidor: 589-593
Publikation/Tidskrift/Serie: Journal of Bioinformatics and Computational Biology
Volym: 2
Nummer: 3
Dokumenttyp: Artikel
Förlag: Imperial College Press / World Scientific Publishing

Sammanfattning

With the ever increasing amount of genomic data available, the interest for generating biochemical pathways has grown tremendously. So far, mainly complete genomes have been used to reconstruct the biochemical pathways and their associated interactions. However, a large number of low coverage genomes, as well as other sources of partial genomic data, are currently available for many organisms. In order to be able to use incomplete data for metabolic reconstruction, the inherent properties of this procedure need to be investigated. In this short note, we describe the robustness and predictive power of metabolic reconstructions using partial information from Schizosaccharomyces pombe. We also discuss the implications of the results on reference genome projects as well as other large-scale sequencing data.

Disputation

Nyckelord

  • Biology and Life Sciences
  • Metabolic reconstruction metabolic maps genome analysis robustness analysis biochemical pathways

Övriga

  • Knut och Alice Wallenbergs Stiftelse
Published
Yes
  • Microbial Ecology
  • ISSN: 0219-7200

Box 117, 221 00 LUND
Telefon 046-222 00 00 (växel)
Telefax 046-222 47 20
lu [at] lu [dot] se

LERU logotype U21 logotype

Fakturaadress: Box 188, 221 00 LUND
Organisationsnummer: 202100-3211
Om webbplatsen