C-reactive protein levels following standard neurosurgical procedures

Summary, in English

Background. The aim of the present study was to establish the magnitude and time-course of C-reactive protein increases following routine neurosurgical procedures in the absence of clinical and laboratory signs of infection. Method. C-reactive protein levels were studied daily following ventriculo-peritoneal shunt implantation, anterior cervical fusion, vestibular schwannoma operation, supratentorial glioma surgery, endovascular intracranial aneurysm treatment and open cerebral aneurysm surgery. Findings. The magnitude of the C-reactive protein increase depended on the extent of surgical trauma and peak-levels were recorded between postoperative day one and four after which the levels tapered off. Interpretation. Increases occur-ring after the fourth postoperative day are likely to be caused by complications of surgery, e.g. infection.

• Författare: Johan Bengzon; Anders Grubb; A Bune; K Hellström; Veronica Lindström; Lennart Brandt
• Avdelning/ar: Neurokirurgi; Avdelningen för klinisk kemi och farmakologi
• Publiceringsår: 2003
• Språk: Engelska
• Sidor: 667-671
• Publikation/Tidskrift/Serie: Acta Neurochirurgica
• Volym: 145
• Issue: 8
• Länkar: http://dx.doi.org/10.1007/s00701-003-0083-5
• Dokumenttyp: Artikel i tidskrift
• Förlag: Springer
• Ämne: Surgery; Medicinal Chemistry; Neurology; Pharmacology and Toxicology
• Nyckelord: C-reactive protein; postoperative; neurosurgery
• Status: Published
• ISBN/ISSN/Övrigt: ISSN: 0001-6268