Novel method for the synthesis of molecularly imprinted polymer bead libraries
Författare
Summary, in English
A novel method for the synthesis of spherical molecularly imprinted polymer (MIP) beads by suspension polymerization in mineral oil is described. The usefulness of the method was demonstrated by the synthesis of a propranolol imprinted MIP library. The composition of the library was generated by statistical experimental design. Multivariate data analysis correlated the screening data, obtained by a radioligand binding assay, to the composition of the MIPs.
Avdelning/ar
Publiceringsår
2004
Språk
Engelska
Sidor
315-320
Publikation/Tidskrift/Serie
Macromolecular Rapid Communications
Volym
25
Issue
1
Dokumenttyp
Artikel i tidskrift
Förlag
John Wiley & Sons Inc.
Ämne
- Pharmacology and Toxicology
Nyckelord
- bead
- spherical
- molecular imprinting
- chemometrics
- combinatorial library
- suspension polymerization
Status
Published
Forskningsgrupp
- Nanomedicine and Biomaterials
ISBN/ISSN/Övrigt
- ISSN: 1022-1336