Reagent-Controlled Cyclization-Deprotection Reaction to Yield either Fluorenes or Benzochromenes

Summary, in English

Compounds with benzochromene and fluorene structures are common in nature and society, and they can have potentially useful biological activities. In this paper, conditions for the selective preparation of either a benzochromene or a fluorene from the same starting material are described. The procedure uses a reagent-controlled cyclization-demethylation to give the benzochromene, or an intramolecular Friedel-Crafts-type alkylation to give the fluorene.

• Författare: Dan Killander; Olov Sterner
• Avdelning/ar: Centrum för analys och syntes
• Publiceringsår: 2014
• Språk: Engelska
• Sidor: 6507-6512
• Publikation/Tidskrift/Serie: European Journal of Organic Chemistry
• Issue: 29
• Länkar: http://dx.doi.org/10.1002/ejoc.201402722
• Dokumenttyp: Artikel i tidskrift
• Förlag: John Wiley & Sons Inc.
• Ämne: Chemical Sciences
• Nyckelord: Cyclization; Chemoselectivity; Aromatic substitution; Nucleophilic; substitution; Oxygen heterocycles; Fused-ring systems
• Status: Published
• ISBN/ISSN/Övrigt: ISSN: 1434-193X