A statistical score for assessing the quality of multiple sequence alignments.

Summary, in English

Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein structures, building phylogenetic trees etc. Although the automatic construction of a multiple sequence alignment for a set of remotely related sequences cause a very challenging and error-prone task, many downstream analyses still rely heavily on the accuracy of the alignments.

• Författare: Virpi Ahola; Tero Aittokallio; Mauno Vihinen; Esa Uusipaikka
• Publiceringsår: 2006
• Språk: Engelska
• Publikation/Tidskrift/Serie: BMC Bioinformatics
• Volym: 7
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/17081313?dopt=Abstract; http://dx.doi.org/10.1186/1471-2105-7-484
• Dokumenttyp: Artikel i tidskrift
• Förlag: BioMed Central (BMC)
• Ämne: Bioinformatics and Systems Biology
• Nyckelord: Computational Biology: methods
• Status: Published
• ISBN/ISSN/Övrigt: ISSN: 1471-2105