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High-throughput proteomics using antibody microarrays

In English

Författare

Summary, in English

Antibody-based microarrays are a novel technology that hold great promise in proteomics. Microarrays can be printed with thousands of recombinant antibodies carrying the desired specificities, the biologic sample (e.g., an entire proteome) and any specifically bound analytes detected. The microarray patterns that are generated can then be converted into proteomic maps, or molecular fingerprints, revealing the composition of the proteome. Using this tool, global proteome analysis and protein expression profiling will thus provide new opportunities for biomarker discovery, drug target identification and disease diagnostics, as well as providing insights into disease biology. Intense work is currently underway to develop this novel technology platform into the high-throughput proteomic tool required by the research community.

Publiceringsår

2004

Språk

Engelska

Sidor

355-364

Publikation/Tidskrift/Serie

Espert Review of Proteomics

Volym

1

Issue

3

Dokumenttyp

Artikel i tidskrift

Förlag

Future Drugs Ltd

Ämne

  • Immunology in the medical area

Status

Published

ISBN/ISSN/Övrigt

  • ISSN: 1744-8387