Fabrication of Microfluidic Platform with Optimized Fluidic Network toward On-Chip Parallel Systematic Evolution of Ligands by Exponential Enrichment Process
Författare
Summary, in English
This paper presents the design and fabrication of a microplatform with the optimal fluidic network for an on-chip parallel "systematic evolution of ligands by exponential enrichment" (SELEX) process. The effectiveness of the optimized fluidic network for on-chip five-plex aptamer screening was verified by measuring the airflow rate at the elution ports and visualizing the specific elution during the SELEX process. The proposed device with an optimally designed hydraulic resistance-balanced channel network could be feasible and utilized as a multiplex selection module for a parallel SELEX process. (c) 2011 The Japan Society of Applied Physics
Avdelning/ar
Publiceringsår
2011
Språk
Engelska
Sidor
05-06
Publikation/Tidskrift/Serie
Japanese Journal of Applied Physics
Volym
50
Issue
6
Dokumenttyp
Artikel i tidskrift
Förlag
IOP Publishing
Ämne
- Medical Engineering
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 0021-4922