Autoantibody profiling can predict primary Sjögren's syndrome years before diagnosis and identify those with early onset and severe disease course.

Summary, in English

Autoantibodies are highly characteristic of primary Sjögren's syndrome (pSS) and represent important tools to study its pathogenesis. Nonetheless, thus far no systematic investigations have assessed the presence of autoantibodies before diagnosis. We analysed how early and in which order these appear, how predictive they are for pSS and if they identify disease subsets.

• Författare: Elke Theander; Roland Jonsson; Bitte Sjöström; Karl Brokstad; Peterx Olsson; Gunnel Henriksson
• Avdelning/ar: Internmedicin - epidemiologi; Klinisk mikrobiologi, Malmö
• Publiceringsår: 2015
• Språk: Engelska
• Sidor: 2427-2436
• Publikation/Tidskrift/Serie: Arthritis & Rheumatology
• Volym: 67
• Issue: 9
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/26109563?dopt=Abstract; http://dx.doi.org/10.1002/art.39214
• Dokumenttyp: Artikel i tidskrift
• Förlag: John Wiley & Sons Inc.
• Ämne: Rheumatology and Autoimmunity
• Status: Published
• Forskningsgrupp: Internal Medicine - Epidemiology; Clinical Microbiology, Malmö
• ISBN/ISSN/Övrigt: ISSN: 2326-5205