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Influence of factor V Leiden on the development of neovascularisation secondary to central retinal vein occlusion.

In English

Författare

Summary, in English

Aims: To investigate if the presence of factor V Leiden has an influence on the prognosis in central retinal vein occlusion (CRVO).



Methods: 166 patients with CRVO were studied retrospectively. They were tested for factor V Leiden using DNA analysis. The presence of the mutation was studied in correlation with the development of neovascular complications 1 year after the thrombotic event.



Results: 56 of 166 patients (34%) developed neovascular complications after 1 year. In the patients who had the studied mutation 11 of 20 (55%) had developed neovascular complications after 1 year, compared to 45 of 146 patients (31%) in the group without factor V Leiden (p=0.04).



Conclusion: The presence of factor V Leiden seems to enhance the risk of developing neovascular complications in CRVO.

Publiceringsår

2003

Språk

Engelska

Sidor

305-306

Publikation/Tidskrift/Serie

British Journal of Ophthalmology

Volym

87

Issue

3

Dokumenttyp

Artikel i tidskrift

Förlag

BMJ Publishing Group

Ämne

  • Ophthalmology
  • Medicinal Chemistry

Status

Published

Forskningsgrupp

  • Clinical Chemistry, Malmö

ISBN/ISSN/Övrigt

  • ISSN: 1468-2079