Novel properties of antimicrobial peptides
Författare
Summary, in English
Endogenous peptide antibiotics are known as evolutionarily old components of innate immunity. Due to interaction with cell membrane these peptides cause permeabilization of the membrane and lysis of invading microbes. However, some studies proved that antimicrobial peptides are universal multifunctional molecules and their functions extend far beyond simple antibiotics. In this review we present an overview of the general mechanism of action of antimicrobial peptides and discuss some of their additional properties, like antitumour activity, mitogenic activity, role in signal transduction pathways and adaptive immune response.
Publiceringsår
2003
Språk
Engelska
Sidor
461-469
Publikation/Tidskrift/Serie
Acta Biochimica Polonica
Volym
50
Issue
2
Dokumenttyp
Artikel i tidskrift
Förlag
Panstwowe Wydawnictwo Naukowe
Ämne
- Other Basic Medicine
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 0001-527X