Expression patterns of two new members of the Semaphorin family in Drosophila suggest early functions during embryogenesis

Summary, in English

We report the sequence and expression analysis of two new Drosophila members of the Semaphorin family. Both proteins show the presence of Semaphorin domains and transmembrane domains. Both genes are expressed maternally and in embryos, and reveal distinct expression patterns much earlier than the onset of neurogenesis. We also present an overview of the domain structure of all so far known semaphorins in Drosophila. Furthermore, we compared all Drosophila and C. elegans Semaphorins and discuss them in the light of their evolution.

• Författare: Narmada Khare; Nora Fascetti; S DaRocha; R Chiquet-Ehrismann; Stefan Baumgartner
• Avdelning/ar: Invertebrate Developmental Biology, Stefan Baumgartner's group
• Publiceringsår: 2000
• Språk: Engelska
• Sidor: 393-397
• Publikation/Tidskrift/Serie: Mechanisms of Development
• Volym: 91
• Issue: 08-01-02
• Länkar: http://dx.doi.org/10.1016/S0925-4773(99)00297-X
• Dokumenttyp: Artikel i tidskrift
• Förlag: Elsevier
• Ämne: Developmental Biology
• Status: Published
• Forskningsgrupp: Invertebrate Developmental Biology, Stefan Baumgartner's group
• ISBN/ISSN/Övrigt: ISSN: 0925-4773