The miR(21/10b) ratio as a prognostic marker in clear cell renal cell carcinoma.

Summary, in English

Clear cell renal cell carcinoma (ccRCC) is the most common type of cancer in the adult kidney, and the prognosis of metastatic ccRCC remains poor with high mortality. In ccRCC, microRNAs (miRs) differentially expressed in tumour tissue have been identified and have been proposed to predict prognosis. The purpose of this study was to evaluate candidate miR markers identified from analysis of The Cancer Genome Atlas (TCGA) datasets in a large RCC cohort and to elucidate whether a ratio of miRs provided additional prognostic information.

• Författare: Helena Fritz; David Lindgren; Börje Ljungberg; Håkan Axelson; Björn Dahlbäck
• Avdelning/ar: Klinisk kemi, Malmö; Avdelningen för translationell cancerforskning; BioCARE: Biomarkers in Cancer Medicine improving Health Care, Education and Innovation
• Publiceringsår: 2014
• Språk: Engelska
• Sidor: 1758-1765
• Publikation/Tidskrift/Serie: European Journal of Cancer
• Volym: 50
• Issue: 10
• Fulltext: - 409 kB; Download statistics
• Länkar: http://www.ncbi.nlm.nih.gov/pubmed/24793999?dopt=Abstract; http://dx.doi.org/10.1016/j.ejca.2014.03.281
• Dokumenttyp: Artikel i tidskrift
• Förlag: Elsevier
• Ämne: Cancer and Oncology
• Status: Published
• Forskningsgrupp: Clinical Chemistry, Malmö
• ISBN/ISSN/Övrigt: ISSN: 1879-0852