Arterial rupture after microwave-induced hyperthermia and radiotherapy. With reference to two patients treated for recurrence in previously operated and irradiated areas
Författare
Summary, in English
Two patients who developed frank arterial bleeding after combined microwave-induced hyperthermia and radiotherapy are described. One patient received re-irradiation and hyperthermia for recurrent metastatic neck nodes of a mesopharyngeal carcinoma. Full course radiotherapy had been given 6 years previously and a right-sided radical neck node dissection had been performed 4 months earlier because of recurrent neck node metastases. Six weeks after the combined therapy for a second recurrence, which achieved complete remission, a fatal rupture of the carotid artery occurred. The other patient received re-irradiation and hyperthermia for a chest wall recurrence of a breast carcinoma, treated 5.5 years previously by sector resection and tangential beam radiotherapy, and treated again 2 years earlier with extensive surgery for a local recurrence. A frank arterial bleeding from the treated region was seen after 7 months, but could be arrested with surgery. This important complication in combined hyperthermia and radiotherapy does not seem to have been recognized before. Different explanations are discussed, such as the previous local treatment as well as high temperature and atherosclerosis per se.
Avdelning/ar
Publiceringsår
1990
Språk
Engelska
Sidor
499-509
Publikation/Tidskrift/Serie
International Journal of Hyperthermia
Volym
6
Issue
3
Dokumenttyp
Artikel i tidskrift
Förlag
Taylor & Francis
Ämne
- Cancer and Oncology
- Radiology, Nuclear Medicine and Medical Imaging
- Cell and Molecular Biology
- Clinical Medicine
Nyckelord
- arterial rupture
- hyperthermia
- complications
Status
Published
Forskningsgrupp
- Pathology, Malmö
ISBN/ISSN/Övrigt
- ISSN: 0265-6736