Enteric neuropathy can be induced by high fat diet in vivo and palmitic Acid exposure in vitro.
Författare
Summary, in English
Obese and/or diabetic patients have elevated levels of free fatty acids and increased susceptibility to gastrointestinal symptoms. Since the enteric nervous system is pivotal in regulating gastrointestinal functions alterations or neuropathy in the enteric neurons are suspected to occur in these conditions. Lipid induced intestinal changes, in particular on enteric neurons, were investigated in vitro and in vivo using primary cell culture and a high fat diet (HFD) mouse model.
Avdelning/ar
- Neurogastroenterology
- Kardiologi
Publiceringsår
2013
Språk
Engelska
Publikation/Tidskrift/Serie
PLoS ONE
Volym
8
Issue
12
Fulltext
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Public Library of Science (PLoS)
Ämne
- Cardiac and Cardiovascular Systems
- Gastroenterology and Hepatology
Status
Published
Forskningsgrupp
- Neurogastroenterology
ISBN/ISSN/Övrigt
- ISSN: 1932-6203