Suicidal patients are deficient in vitamin D, associated with a pro-inflammatory status in the blood.
Författare
Summary, in English
Low levels of vitamin D may play a role in psychiatric disorders, as cross-sectional studies show an association between vitamin D deficiency and depression, schizophrenia and psychotic symptoms. The underlying mechanisms are not well understood, although vitamin D is known to influence the immune system to promote a T helper (Th)-2 phenotype. At the same time, increased inflammation might be of importance in the pathophysiology of depression and suicide. We therefore hypothesized that suicidal patients would be deficient in vitamin D, which could be responsible for the inflammatory changes observed in these patients.
Publiceringsår
2014
Språk
Engelska
Sidor
210-219
Publikation/Tidskrift/Serie
Psychoneuroendocrinology
Volym
50
Fulltext
- Available as PDF - 709 kB
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Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Elsevier
Ämne
- Medicinal Chemistry
- Psychiatry
Status
Published
Projekt
- Individanpassad behandling av patienter med depression, med särskilt fokus på suicidrisk.
Forskningsgrupp
- Clinical Chemistry, Malmö
- Unit for clinical suicide research
ISBN/ISSN/Övrigt
- ISSN: 1873-3360