LUBIRC Breakfast Seminar – Magnus Carlquist
Engineering microbial cells for the production of bio-amines
LUBIRC would like to invite you our next breakfast seminar, given by Dr Magnus Carlquist. From the Division of Applied Microbiology at LU, Magnus specialises in biocatalysis and enzyme technology. In his own words, the seminar will cover:
Primary alkylamines and lactams are important bulk chemicals in the chemical industry, used for the production of various consumer products including medicines, textiles, and plastics. They are produced today on the scale of multimillions of tonnes per year by refining crude oil through energy-demanding chemo-catalytic processes with large environmental footprints. Sustainable methods that follow the 12 design principles of Green Chemistry are urgently needed.
Analogous to a petrochemical refinery that transforms crude oil into various platform chemicals, microbial cells can be metabolically engineered to transform renewable substrates into the same platform chemicals by fermentation.
This seminar will provide a deep-dive into how to engineer microbial cells into becoming amine-producing cell factories. The focus will be on engineering amine transaminase activity in vivo in yeast and bacteria. Applications for reductive amination of aromatic ketones and aldehydes derived from technical lignin will be discussed.
Please note that this LUBIRC seminar will be held via Microsoft Teams. The link to connect to the seminar will be provided upon registration. Please register with the following form: registration
(Föredraget hålls på engelska)
A warm welcome to all!