Economic Evaluation of Smoking-Cessation Therapies: A Critical and Systematic Review of Simulation Models.
Författare
Summary, in English
Background: Smoking is probably the most important among preventable health risks. Health economic evaluation of smoking-cessation interventions, applying a lifetime perspective, is made possible by available epidemiological knowledge. The well established method of performing cost-effectiveness analyses of smoking-cessation interventions involves mathematical modelling (both deterministic and stochastic) of future events important for cost effectiveness. Objectives: This study surveys cost-effectiveness analyses of smoking cessation, with a particular focus on the mathematical modelling and simulation analyses performed. Data Sources: A systematic literature search was performed using the databases MEDLINE, Econlit and Academic Search Complete. Study Selection: Health economic evaluations, published as full-length journal articles, were searched for. Results: 423 studies were identified and 78 were finally included, of which 30 were assessed as being highly relevant, based on the application of simulation modelling. Conclusions: In general, studies are well performed as regards modelling. Common weaknesses include reporting of modelling details; validation of used simulation models; and the handling of structural uncertainty and different types of heterogeneity.
Avdelning/ar
Publiceringsår
2012
Språk
Engelska
Sidor
551-564
Publikation/Tidskrift/Serie
PharmacoEconomics
Volym
30
Issue
7
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
Adis International
Ämne
- Economics
Status
Published
ISBN/ISSN/Övrigt
- ISSN: 1179-2027