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Ultrahydrophobic properties of porous silicon for surface based bioanalysis

  • Viovy Jean-Louis
  • Patrick Tabeling
  • Stephanie Descroix
  • Laurent Malaquin
Publiceringsår: 2007
Språk: Engelska
Sidor: 1046-1047
Publikation/Tidskrift/Serie: Micro Total Analysis Systems 2007, Proceedings of µTAS 2007 Conference
Volym: 2
Dokumenttyp: Konferensbidrag
Förlag: Chemical and Biological Microsystems Society


Previously we reported the extreme water repellency of randomly organized macro-/nanoporous silicon surfaces [1]. The texturized silicon with hierarchical porous structure in micrometer and nanometer scale was shown to exhibit the superhydrophobic behaviour. Contact angles as high as 176º can be easily achieved with further fluoroalkylsilane modification of the porous surfaces. Porous silicon technology is compatible with the silicon patterning techniques allowing easy integration of the ultrahydrophobic properties into microfluidic and lab-on-a-chip devices for a new generation of surface based bioanalysis. In this paper we report the fabrication of ultrahydrophobic porous silicon channels and ultrahydrophobic nanovial arrays. Also the MALDI-TOF MS (matrix assisted laser desorption/ionization time-of-flight mass-spectrometry) target anchor chip composed of the hydrophilic anchor points for sample deposition surrounded by the ultrahydrophobic porous area is reported. Such anchor chip allowed the deposition of large sample volumes providing the strategy to improve MALDI-TOF MS sensitivity.


  • Medical Engineering
  • Analytical Chemistry
  • water repellency
  • porous silicon
  • superhydrophobic
  • microfluidics


Eleventh International Conference on Miniaturized Systems for Chemistry and Life Sciences
  • ISBN: 978-0-9798064-0-7

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