Robustness of metabolic maps
Författare
Summary, in English
With the ever increasing amount of genomic data available, the interest for generating biochemical pathways has grown tremendously. So far, mainly complete genomes have been used to reconstruct the biochemical pathways and their associated interactions. However, a large number of low coverage genomes, as well as other sources of partial genomic data, are currently available for many organisms. In order to be able to use incomplete data for metabolic reconstruction, the inherent properties of this procedure need to be investigated. In this short note, we describe the robustness and predictive power of metabolic reconstructions using partial information from Schizosaccharomyces pombe. We also discuss the implications of the results on reference genome projects as well as other large-scale sequencing data.
Avdelning/ar
Publiceringsår
2004
Språk
Engelska
Sidor
589-593
Publikation/Tidskrift/Serie
Journal of Bioinformatics and Computational Biology
Volym
2
Issue
3
Dokumenttyp
Artikel i tidskrift
Förlag
World Scientific Publishing
Ämne
- Biological Sciences
Nyckelord
- Metabolic reconstructionmetabolic mapsgenome analysisrobustness analysisbiochemical pathways
Status
Published
Forskningsgrupp
- Microbial Ecology
ISBN/ISSN/Övrigt
- ISSN: 0219-7200