Immigrant status and increased risk of heart failure: the role of hypertension and life-style risk factors

Author

Summary, in English

Background: Studies from Sweden have reported association between immigrant status and incidence of cardiovascular diseases. The nature of this relationship is unclear. We investigated the relationship between immigrant status and risk of heart failure (HF) hospitalization in a population-based cohort, and to what extent this is mediated by hypertension and life-style risk factors. We also explored whether immigrant status was related to case-fatality after HF. Methods: 26,559 subjects without history of myocardial infarction (MI), stroke or HF from the community-based Malmo Diet and Cancer (MDC) cohort underwent a baseline examination during 1991-1996. Incidence of HF hospitalizations was monitored during a mean follow-up of 15 years. Results: 3,129 (11.8%) subjects were born outside Sweden. During follow-up, 764 subjects were hospitalized with HF as primary diagnosis, of whom 166 had an MI before or concurrent with the HF. After adjustment for potential confounding factors, the hazard ratios (HR) for foreign-born were 1.37 (95% CI: 1.08-1.73, p = 0.009) compared to native Swedes, for HF without previous MI. The results were similar in a secondary analysis without censoring at incident MI. There was a significant interaction (p < 0.001) between immigrant status and waist circumference (WC), and the increased HF risk was limited to immigrants with high WC. Although not significant foreign-born tended to have lower one-month and one-year mortality after HF. Conclusions: Immigrant status was associated with long-term risk of HF hospitalization, independently of hypertension and several life-style risk factors. A significant interaction between WC and immigrant status on incident HF was observed.

Publiceringsår

2012

Language

Engelska

Publikation/Tidskrift/Serie

BMC Cardiovascular Disorders

Volym

12

Issue

20

Dokumenttyp

Artikel i tidskrift

Förlag

BioMed Central

Ämne

  • Cardiac and Cardiovascular Systems

Nyckelord

  • Immigrant status
  • heart failure
  • risk factors
  • cohort study
  • case
  • fatality
  • epidemiology

Status

Published

Forskningsgrupp

  • Cardiovascular Research - Epidemiology

ISBN/ISSN/Övrigt

  • ISSN: 1471-2261