Computational Perspectives on Neuromodulation of Aging
Författare
Summary, in English
Cognitive functions, such as memory, attention, and perception, declines with age. Besides other neuroanatomical changes, the level of dopamine also attenuates during aging. We review how computational modeling can provide insights in how these lifetime changes in dopamine levels is expressed at the behavioral level yielding a bridge across different levels. Results indicate that attenuation of dopamine lowers the signal to noise ratio providing a less distinctive neural representation, and detrimental cognitive performance.
Avdelning/ar
Publiceringsår
2007
Språk
Engelska
Sidor
513-518
Publikation/Tidskrift/Serie
Acta Neurochirurgica. Supplementum
Volym
97
Dokumenttyp
Artikel i tidskrift
Förlag
Springer
Ämne
- Psychology (excluding Applied Psychology)
Nyckelord
- cognitive functions
- neural networks
- aging
- neuromodulation
- Dopamine
- noise
Status
Published
Forskningsgrupp
- Lund University Cognitive Science (LUCS)
ISBN/ISSN/Övrigt
- ISSN: 0065-1419