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Quantitative analysis of circadian variation in atrial fibrillation frequency

Publiceringsår: 2009
Språk: Engelska
Sidor: 129-132
Publikation/Tidskrift/Serie: [Host publication title missing]
Volym: 36
Dokumenttyp: Konferensbidrag
Förlag: IEEE--Institute of Electrical and Electronics Engineers Inc.


Circadian variation in atrial fibrillation (AF) frequency

is explored in this paper by employing recent advances in

signal processing. Once the AF frequency has been estimated

and tracked by a hidden Markov model approach,

the resulting trend is analyzed for the purpose of detecting

and characterizing the presence of circadian variation.

With cosinor analysis, the results show that the shortterm

variations in AF frequency exceeds the variation that

may be attributed to circadian. Using the autocorrelation

method, circadian variation was detected in 13 of 18

ambulatory ECG recordings (Holter) acquired from patients

with long standing persistent AF. Using the ensemble

correlation method, the highest AF frequency usually occurred

during the afternoon, whereas the lowest usually

occurred during late night. It is concluded that circadian

variation is present in most patients with long standing

persistent AF but the short-term variation in AF frequency

is considerable.


  • Electrical Engineering, Electronic Engineering, Information Engineering


36th Annual Computers in Cardiology Conference, 2009
  • Signal Processing-lup-obsolete

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