Valeriya Lyssenko
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+4640391214
Valeriya [dot] Lyssenko [at] med [dot] lu [dot] se
Publikationer (hämtat ur Lunds universitets publikationsdatabas)
författare
- 2013
- 2012
- A common variant upstream of the PAX6 gene influences islet function in man.
- A genome-wide approach accounting for body mass index identifies genetic variants influencing fasting glycemic traits and insulin resistance
- A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
- Codon 72 polymorphism (rs1042522) of TP53 is associated with changes in diastolic blood pressure over time
- Common variant in the HMGA2 gene increases susceptibility to nephropathy in patients with type 2 diabetes.
- Effect of a common variant of the PCSK2 gene on reduced insulin secretion.
- Genetic Variation in the Glucose-Dependent Insulinotropic Polypeptide Receptor Modifies the Association between Carbohydrate and Fat Intake and Risk of Type 2 Diabetes in the Malmo Diet and Cancer Cohort.
- Genetic prediction of postpartum diabetes in women with gestational diabetes mellitus
- Kartläggning av skyddsfaktorer vid typ 1-diabetes har börjat. Vissa patienter tycks skyddade mot sena komplikationer--flera studier pågår.
- Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
- No Interactions Between Previously Associated 2-Hour Glucose Gene Variants and Physical Activity or BMI on 2-Hour Glucose Levels
- Reduced Insulin Exocytosis in Human Pancreatic β-cells With Gene Variants Linked to Type 2 Diabetes.
- Regulation of the pro-inflammatory cytokine osteopontin by GIP in adipocytes - A role for the transcription factor NFAT and phosphodiesterase 3B.
- Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
- The human L-type calcium channel Ca(v)1.3 regulates insulin release and polymorphisms in CACNA1D associate with type 2 diabetes.
- Tired of Diabetes Genetics? Circadian Rhythms and Diabetes: The MTNR1B Story?
- Validation of a multi-marker model for the prediction of incident type 2 diabetes mellitus: Combined results of the Inter99 and Botnia studies.
- 2011
- A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes.
- Association between parental history of diabetes and type 2 diabetes genetic risk scores in the PPP-Botnia and Framingham Offspring Studies
- FTO, Type 2 Diabetes, and Weight Gain Throughout Adult Life A Meta-Analysis of 41,504 Subjects From the Scandinavian HUNT, MDC, and MPP Studies
- Genome-Wide Association Identifies Nine Common Variants Associated With Fasting Proinsulin Levels and Provides New Insights Into the Pathophysiology of Type 2 Diabetes
- Heritability and familiality of type 2 diabetes and related quantitative traits in the Botnia Study.
- Pleiotropic Effects of GIP on Islet Function Involve Osteopontin
- Power in the Phenotypic Extremes: A Simulation Study of Power in Discovery and Replication of Rare Variants
- 2010
- A common variant in the PAX6 gene influences islet function in man
- A family history of diabetes is associated with reduced physical fitness in the Prevalence, Prediction and Prevention of Diabetes (PPP)-Botnia study
- A meta-analysis of GWA blood glucose after 2 h of OGTT revealed that GIPR is associated with the secretion of insulin based on glucose and ADCY5 is a new susceptibility gene for type 2 diabetes.
- Analysis of TBC1D4 in patients with severe insulin resistance
- Detailed Physiologic Characterization Reveals Diverse Mechanisms for Novel Genetic Loci Regulating Glucose and Insulin Metabolism in Humans
- Effect of variants in the RORA gene on risk of type 2 diabetes
- Erratum to: Assessing the effect of interaction between an FTO variant (rs9939609) and physical activity on obesity in 15,925 Swedish and 2,511 finnish adults.
- GAD Antibody Positivity Predicts Type 2 Diabetes in an Adult Population
- Genetic susceptibility for obesity increases the risk of type 2 diabetes and is modified by macronutrient intakes
- Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge
- Genome wide association analysis for free fatty acid levels in DGI
- Influence of novel genetic loci affecting glucose and insulin levels during OGTT on islet function in man
- Minimal Contribution of Fasting Hyperglycemia to the Incidence of Type 2 Diabetes in Subjects With Normal 2-h Plasma Glucose
- New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
- Polymorphisms in CACNA1D affect insulin release and channel expression and associate with type 2 diabetes
- The shape of plasma glucose concentration curve during OGTT predicts future risk of type 2 diabetes
- Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis
- 2009
- A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion.
- Assessing the effect of interaction between an FTO variant (rs9939609) and physical activity on obesity in 15,925 Swedish and 2,511 Finnish adults.
- Disruption of TFB1M impairs insulin secretion in beta cells
- Fasting Versus Postload Plasma Glucose Concentration and the Risk for Future Type 2 Diabetes Results from the Botnia Study
- Functional Variant Disrupts Insulin Induction of USF1 Mechanism for USF1-Associated Dyslipidemias
- Genetic basis of beta-cell dysfunction in man.
- Genetics of type 2 diabetes. An overview.
- Genetics of type 2 diabetes. On overview.
- Genome-wide association study for type 2 diabetes: clinical applications.
- Genome-wide meta-analysis identifies novel genetic loci associated with OGTT-induced post-challenge glucose
- Hyperactivity in adrenergic signalling via alpha2A receptors contributes to human type 2 diabetes
- Interaction between prenatal growth and high-risk genotypes in the development of type 2 diabetes
- Melatonin receptors in pancreatic islets: good morning to a novel type 2 diabetes gene.
- Prioritizing genes for follow-up from genome wide association studies using information on gene expression in tissues relevant for type 2 diabetes mellitus
- The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men
- The diabetes risk score outperforms fasting plasma glucose and glucose tolerance tests: combined results from the Inter99 and Botnia Studies
- Underlying Genetic Models of Inheritance in Established Type 2 Diabetes Associations
- Variants in MTNR1B influence fasting glucose levels
- 2008
- Clinical risk factors, DNA variants, and the development of type 2 diabetes.
- Common Missense Variant in the Glucokinase Regulatory Protein Gene Is Associated With Increased Plasma Triglyceride and C-Reactive Protein but Lower Fasting Glucose Concentrations
- Common variants in maturity-onset diabetes of the young genes and future risk of type 2 diabetes
- Common variants in or around the JAZF1, CDKN2A/2B, CDKAL1 and WFS1 genes discriminate between autoimmune and non-autoimmune diabetes
- Genetic analysis of recently identified type 2 diabetes loci in 1,638 unselected patients with type 2 diabetes and 1,858 control participants from a Norwegian population-based cohort (the HUNT study)
- Genetic similarities between latent autoimmune diabetes in adults, type 1 diabetes, and type 2 diabetes
- Identification of ten loci associated with height highlights new biological pathways in human growth
- Interactions between genes and birth size for development of type 2 diabetes
- Is there a unifying genetic factor predisposing to the metabolic syndrome?
- Meta-analysis of genome-wide association data and large-scale replication identifies additional susceptibility loci for type 2 diabetes
- Metabolic effects of novel type 2 diabetes genes in a population aged 18-75 years
- The Pro12Ala polymorphism of the PPAR-gamma2 gene affects associations of fish intake and marine n-3 fatty acids with glucose metabolism
- The search for putative unifying genetic factors for components of the metabolic syndrome.
- The transcription factor 7-like 2 gene and increased risk of type 2 diabetes: an update.
- Variants in KCNQ1 are associated with susceptibility to type 2 diabetes mellitus
- Variations in the G6PC2/ABCB11 genomic region are associated with fasting glucose levels.
- 2007
- Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
- Mechanisms by which common variants in the TCF7L2 gene increase risk of type 2 diabetes.
- Polymorphisms in the gene encoding the voltage-dependent Ca(2+) channel Ca (V)2.3 (CACNA1E) are associated with type 2 diabetes and impaired insulin secretion
- Variants in the FFAR1 Gene Are Associated with Beta Cell Function
- 2006
- Analysis of the interleukin-1 and interleukin-6 polymorphisms in patients with chronic periodontitis. A pilot study
- Authors' reply.
- Common single nucleotide polymorphisms in TCF7L2 are reproducibly associated with type 2 diabetes and reduce the insulin response to glucose in nondiabetic individuals
- Common variants in HNF-1 alpha and risk of type 2 diabetes.
- IL6 gene promoter polymorphisms and type 2 diabetes - Joint analysis of individual participants' data from 21 studies
- 2005
