046-222 64 33
072-549 47 00
Christer [dot] Larsson [at] med [dot] lu [dot] se
Publikationer (hämtat ur Lunds universitets publikationsdatabas)
- New insights into PKC family affairs: three novel phosphorylation sites in PKCepsilon and at least one is regulated by PKCalpha.
- PKCepsilon binds peripherin and induces its aggregation which is accompanied by apoptosis of neuroblastoma cells.
- Protein kinase Cepsilon is important for migration of neuroblastoma cells
- Arsenic trioxide-induced neuroblastoma cell death is accompanied by proteolytic activation of nuclear Bax.
- Comparison of the PKCalpha and the PKCepsilon C1b Domains: Identification of Residues Critical for PKCepsilon-mediated Neurite Induction.
- Identification of acidic amino acid residues in the PKCalpha V5 domain that contribute to its insensitivity to diacylglycerol.
- Identification of acidic amino acid residues in the protein kinase C alpha V5 domain that contribute to its insensitivity to diacylglycerol
- A possible role for p190RhoGAP in PKCepsilon-induced morphological effects.
- Autophosphorylation suppresses, whereas kinase inhibition augments, the translocation of PKCa in response to diacylglycerol.
- Ceramide influences neurite outgrowth and neuroblastoma cell apoptosis regulated by novel protein kinase C isoforms.
- Identification of an amino acid residue in the PKC C1b domain crucial for its localisation to the Golgi network.
- Induction of neurites by the regulatory domains of PKCdelta and epsilon is counteracted by PKC catalytic activity and by the RhoA pathway.
- Regulation of ADAM12 cell-surface expression by protein kinase C epsilon
- The V5 domain of protein kinase C plays a critical role in determining the isoform-specific localization, translocation, and biological function of protein kinase C-delta and -epsilon
- A protein kinase Cbeta inhibitor attenuates multidrug resistance of neuroblastoma cells.
- ADAM12/syndecan-4 signaling promotes beta(1) integrin-dependent cell spreading through protein kinase C alpha and RhoA
- Expression of trkB in Human Neuroblastoma in Relation to MYCN Expression and Retinoic Acid Treatment.
- The catalytic domain limits the translocation of protein kinase C alpha in response to increases in Ca2+ and diacylglycerol.
- The regulatory domain of protein kinase Ctheta localises to the Golgi complex and induces apoptosis in neuroblastoma and Jurkat cells.
- A role for PKC-epsilon in Fc gamma R-mediated phagocytosis by RAW 264.7 cells
- Leukotriene D(4) activates MAPK through a Ras-independent but PKCepsilon-dependent pathway in intestinal epithelial cells.
- Leukotriene D-4 activates MAPK through a Ras-independent but PKC epsilon-dependent pathway in intestinal epithelial cells
- Leukotriene D-4 induces stress-fibre formation in intestinal epithelial cells via activation of RhoA and PKC delta
- Protein Kinase Cepsilon Actin-binding Site Is Important for Neurite Outgrowth during Neuronal Differentiation.
- A PKCbeta isoform mediates phorbol ester-induced activation of Erk1/2 and expression of neuronal differentiation genes in neuroblastoma cells
- ADAM 12-induced syndecan-beta 1 integrin mediated cell spreading is regulated by protein kinase C alpha, PI-3 kinase and Rac
- Differences in early and late responses between neurotrophin-stimulated trkA- and trkC-transfected SH-SY5Y neuroblastoma cells
- The epsilon isoform of protein kinase C is involved in regulation of the LTD(4)-induced calcium signal in human intestinal epithelial cells
- Human achaete-scute homologue 1 (HASH-1) is downregulated in differentiating neuroblastoma cells
- Novel and classical protein kinase C isoforms have different functions in proliferation, survival and differentiation of neuroblastoma cells
- PKCepsilon, via its regulatory domain and independently of its catalytic domain, induces neurite-like processes in neuroblastoma cells
- The basic helix-loop-helix transcription factor dHAND, a marker gene for the developing human sympathetic nervous system, is expressed in both high- and low-stage neuroblastomas
- Acute ethanol exposure attenuates expression of junD in human neuroblastoma cells
- Carbachol-stimulated Ca2+ increase in single neuroblastoma SH-SY5Y cells: effects of ethanol
- Ethanol exposure potentiates fosB and junB expression induced by muscarinic receptor stimulation in neuroblastoma SH-SY5Y cells
- Stimulation of muscarinic receptors induces expression of individual fos and jun genes through different transduction pathways
- Acute effects of D-1 and D-2-receptor agonist and antagonist drugs on somatostatin binding, inhibition of adenylyl cyclase activity and accumulation of inositol 1,4,5-trisphosphate in the rat striatum
- Characterization of phospholipase D activation by muscarinic receptors in human neuroblastoma SH-SY5Y cells
- Effects of ethanol on muscarinic receptor-stimulated c-fos expression in human neuroblastoma cells
- An okadaic acid-sensitive protein phosphatase counteracts protein kinase C-induced phosphorylation in SH-SY5Y cells
- Desensitization of acetylcholine induced inositol 1,4,5-trisphosphate formation in neuroblastoma SH-SY5Y cells following repetitive acetylcholine stimulations
- Evaluation of ethanol effects on PLC signal transduction pathways using cell lines of neuronal origin