DNA methylation of the glucagon-like peptide 1 receptor (GLP1R) in human pancreatic islets.
Författare
Summary, in English
Insulin secretion is enhanced upon the binding of Glucagon-like peptide-1 (GLP-1) to its receptor (GLP1R) in pancreatic β cells. Although a reduced expression of GLP1R in pancreatic islets from type 2 diabetic patients and hyperglycaemic rats has been established, it is still unknown if this is caused by differential DNA methylation of GLP1R in pancreatic islets of type 2 diabetic patients.
Avdelning/ar
Publiceringsår
2013
Språk
Engelska
Publikation/Tidskrift/Serie
BMC Medical Genetics
Volym
14
Issue
Jul,23
Fulltext
- Available as PDF - 683 kB
- Download statistics
Länkar
Dokumenttyp
Artikel i tidskrift
Förlag
BioMed Central (BMC)
Ämne
- Medical Genetics
Status
Published
Forskningsgrupp
- Translational Muscle Research
- Diabetes - Epigenetics
ISBN/ISSN/Övrigt
- ISSN: 1471-2350